This blog tracks updates to the Blood Sugar 101 Web site.

Wednesday, August 26, 2009

FDA Adds More Drugs to List of Those that Combine with Glyburide to Cause Hypos

Page changed: Metformin, Acarbose, and Drugs that Stimulate Insulin Secretion

Added this text:

The following drugs are known to increase the effect of sulfonylurea drugs which can cause dangerous hypos:

Nonsteroidal anti-inflammatory drugs [Ibuprofen, Motril, Advil etc], clarithromycin, and other drugs that are highly protein bound, such as salicylates [aspirin], sulfonamides [Septra, Bactrim, etc], chloramphenicol, coumarins, probenecid, monoamine oxidase inhibitors, and ß-adrenergic blocking agents [Beta Blockers like Toprol and others].

In August of 2009 The FDA added a new warning about combining Glyburide with disopyramide [Norpace], fluoxetine [Prozac], and quinolones [Cipro and other "floxin" antibiotics].

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