This blog tracks updates to the Blood Sugar 101 Web site.

Monday, July 11, 2011

NSAIDS Linked to Increased Incidence of Atrial Fibrillation Especially in People with Kidney Disease

Page Changed: Other Dangerous Drugs for People with Diabetes

Added the following:

NSAIDS (Advil, Ibuprofen, Celebrex, etc.) Linked to Higher Risk of Atrial Fibrillation

Evidence from a study of 32,602 patients from the Danish National Registry found that a history of taking first generation Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) such as Advil or ibuprofen was associated with a 40% higher risk of developing an abnormal heart rhythm.The newer COX-2 inhibitors like Celebrex were associated with a 70% higher risk.The risk was greatest for older people and people with kidney disease. This makes it likely that these drugs are more dangerous for people with Diabetes, many of whom have signs of kidney damage.

Non-steroidal anti-inflammatory drug use and risk of atrial fibrillation or flutter: population based case-control study. M. Schmidt, et al. BMJ, 2011; 343 (jul04 1): d3450 DOI: 10.1136/bmj.d3450

Discussed in detail here:

Science Daily: Common Pain Killers Linked to Irregular Heart Rhythm