This blog tracks updates to the Blood Sugar 101 Web site.

Tuesday, November 25, 2008

More Evidence Later Onset LADA Shares Common Gene with Type 2

Page changed: LADA -- Slow Onset Type 1

Added second study that finds that the incidence of the diabetic allele of TCF7L2 is similar in people over the age of 40 diagnosed as being GAD positive (i.e. having autoimmune diabetes) as it is in GAD negative Type 2s. This strengthens the concept that LADA that comes on in middle age may be a combined form of Type 1 and Type 2.

It's worth keeping in mind, though, that the presence of the antibodies mean that an autoimmune attack is present and the person diagnosed with LAD often ends up fully insulin dependent and prone to DKA without insulin.

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