Generic repaglinide may act much more slowly than Prandin, making hypos more likely

Page Changed: Glipizide, Glyburide, Repaglinide etc: Drugs that Stimulate Insulin Secretion

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Generic Repaglinide May Not Have the Same Speed of Action as Name Brand Prandin

By using a FreeStyle Libre Flash Glucose Monitor, I was able to see exactly how repaglinide works for me, and discovered that it appears to activate much more slowly than the brand name Prandin version that I used to use before the drug was available as a generic. My pharmacist confirms this is likely. If your insurance will let your doctor prescribe the name brand version, use it. Otherwise, you may have to take repaglinide 1 to 2 hours before eating to get it to lower the peak caused by a meal. If you take it at meal time, as directed by the label, you may get a peak one hour after eating, followed by a potentially serious low an hour or two later. The branded version can be taken at mealtimes and peaks at 1 hour after it is taken.