This blog tracks updates to the Blood Sugar 101 Web site.

Thursday, June 11, 2009

Confirmation of Causative Link of Avandia and Actos to Fractures and Heart Failure

Page Changed: Avandia and Actos: Dangerous Diabetes Drugs

Added information from three new studies, two presented at ADA and one described in Science News based on German publication which confirm these drugs double risk of heart failure and cause fractures in both men and women. The German study explains the underlying mechanism by which Avandia and Actos cause heart failure. Stimulating PPAR-gamma turns out to change the way the heart metabolises fats in a way that weakens heart muscle.

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