This blog tracks updates to the Blood Sugar 101 Web site.

Saturday, November 1, 2014

New SGLT2 combo drugs approved, and more side effects discovered

Page Changed: SGLT2 Inhibitors, Farxiga, Invokana, Jardiance. Questionable New Drugs

Added this text:
p >These sodium-glucose co-transporter-2 (SGLT-2) inhibitors lower blood sugar by blocking reabsorption of glucose by the kidney and increasing its excretion in urine. However, recent findings suggest tht though these drugs ramp up excretion of glucose, they also ramp up production of glucose by stimulating the secretion of glucagon. More about that can be read HERE


The web site describing this class of drugs also says that in the studies used for approving the drug there were more cases of liver failure, breast and bladder cancer, though the effect was not strong enough to block approval of the drug. Added mention of Invokamet and Xigduo, combination forms of these drugs with metformin.

Monday, October 27, 2014

Changes to the "What is a Normal Blood Sugar" page

Page Changed: What is a Normal Blood Sugar

Added this text:

What is an Abnormally Low Blood Sugar?
Blood sugars under 70 mg/dl (3.9 mmol/L) are considered to be hypoglycemic and should be avoided.
If you are not on insulin or a drug that causes your pancreas to secrete insulin, a blood sugar 5 to 10 mg/dl slightly below this range, while it might be uncomfortable, is not dangerous unless there is evidence that it is continuing to drop. This is because home blood sugar meters often read lower than lab values, so a reading in that very slightly lower range might actually be normal.
However, if you are using insulin or a drug that causes your body to secrete insulin (described HERE you must err on the side of caution and keep your blood sugar well over 70 mg/dl (3.9 mmol/L).
This is because home meters may also read higher than your actual blood sugar so your 70 mg/dl reading may actually be 62 mg/dl. Even more importantly, the insulin or oral drug that has lowered your blood sugar to this level may still be working to lower your blood sugar even more. So if you don't treat a reading near 70 mg/dl, it may go on to drop to a dangerouly low level.


Added this section:

Normal Blood Sugars in Pregnancy

Because the blood volume increases greatly during pregnancy, diluting blood sugar, normal blood sugar concentrations for pregnant women are lower than those for everyone else.

Based on current research, normal pregnant women's blood sugar falls into this range:
Fasting: 70.9 ± 7.8 mg/dl (3.94 mmol/L ± .43)
One Hour Post Meal: 108.9 ± 12.9 mg/dl (6.05 ± .72 mmol/L)
Two Hours Post Meal: 99.3 ±10.2 mg/dl (5.52 ± .57 mmol/L )

Pregant women with diabetes should strive for these blood sugars:
Fasting: 79 mg/dl (4.4 mmol/L)
One Hour After Meals: 122 mg/dl (6.8 mmol/L)
Two Hours After Meals: 110 m/gdl (6.1 mmol/L)

You can learn about the studies that established these values HERE

Wednesday, September 3, 2014

New $.99 Kindle Short Read: How to Lower Your Blood Sugar

Page Changed: Jenny Ruhl's Books

Added this text:

Download the 30 Minute Kindle Short Read that Teaches the Essentials of Blood Sugar Control
This e-booklet:

Sunday, August 3, 2014

Jardiance: Another SGLT-2 Inhibitor Is Approved

Page Changed: Invokana, Farxiga, Jardiance: A New Class of Questionable Drugs for Type 2 Text Added: Jardiance is the same empagliflozin that the FDA did not approve a year ago supposedly because of unspecified manufacturing problems. It was approved in August 2014. Like the other drugs we just discussed Jardiance causes urinary tract infections and vaginal, and penile yeast infection. The FDA is also demanding post-marketing cardiovascular tests, so it is likely that the same disturbing signals emerged in its clinical trials as emerged with the other drugs. It too is not recommended for people with kidney disease. It is not known whether a cancer signal appeared in its clinical trials. But since these trials only involved a total of 4,500 people and did not last more than a few years, the cancer signal seen in other drugs in the same class should not be ignored.

Tuesday, July 29, 2014

Farxiga, Another Recently Approved Questionable Type 2 Drug

Page Changed: Invokana and Farxiga: Members of a New Class of Dangerous Drugs for Type 2

Added Text:

Farxiga, a Second, Even Worse Drug in this Same Class

Farxiga, mysteriously named "Forxiga" outside of the U.S., is a second drug in this same SGLT-2 inibitor class, which has all the same side efects as Invokana, along with the possibility that it increases LDL-C, the so called "bad" cholesterol.

There were more cases of bladder cancer among those taking it than in the group that did not take it. AstraZeneca, the company selling it, assures you that the numbers in the study were too small to determine if this was statistically significant. Why would you want to participate in the much larger and, to AstraZeneca highly profitable" "study" conducted on paying human lab rats that will, by the time the patent expires on this drug, make it crystal clear just how dangerous it really is?

Saturday, June 28, 2014

Page changed: Insulin for Type 2 Diabetes

Added this text:

Inhaled Insulin

A new inhaled insulin, Afrezza, was approved by the FDA on June 27, 2014. You can read more about it HERE. More information will be posted as more information about this brand new drug becomes known.

Wednesday, May 14, 2014

FDA Warns Against Using GenStrips

Page Changed: Diabetes on a Budget

Text Modified: If you use an older One Touch Ultra or an One Touch Mini which allows you to set and change the strip code, there are two brands of generic test strips available now that will work with these meters while costing far less than the brand name strips. Both can be purchased from Amazon.
The first is Genstrips . Unfortunately, the FDA issued a warning in April 2014 stating that these strips were not accurate and that the manufacturer had failed quality inspections. When I used these strips last year, they worked well, but reviewers on Amazon who had the same experience said newer strips gave really bad readings. Even less expensive are the UniStrip Test Strips. I have not tested these, but the research used by the company to secure FDA approval makes them appear to also be as accurate as the branded strips. Let's hope that continues to be the case.

NOTE:  I have received a lot of mail from readers of my blog who received an email from Amazon warning about the FDA warning about Genstrips and I updated the blog post and Blood Sugar 101 web page that described these strips as soon as I received the same letter.  Unfortunately, I forgot to post the update on this blog for those of you who follow changes to the changes to the blog.