Vitamin D Supplementation Greatly Improves Chronic Kidney Disease Outcome

Page Changed: Supplements that Work

Added reference to newly published journal study showing a 26% reduction in mortality and a 20% reduction in progression to dialysis in kidney disease patients taking calcitriol, a form of Vitamin D.

Dr. Goldstein Documents Januvia's Connection with Colon and Prostate Cancer iin Annals of Internal Medicine

Page changed: Januvia

Added citation to the letter from Dr. Mark R. Goldstein published in the September 2007 Annals of Internal Medicine documenting studies showing a connection between colon and prostate cancer and DPP-4 inhibition--the mechanism by which Januvia stimulates insulin release.

If your doctor prescribes Januvia, ask him if he is aware of this research and if not, make him aware of it. With its ability to promote cancer, and the complete ignorance of most doctors of what exactly it is that Januvia does, Januvia may well end up being the Thalidomide of the 2000s.

And if you are taking Januvia and are diagnosed with cancer, insist that your doctor file an aftermarket report with the FDA Medwatch system!

Genetic Study of LADA Finds Genes Associated with Both Type 1 and Type 2 Diabetes

Page Changed: LADA: Slow Onset Type 1 Diabetes with Some Type 2 Features

Added discussion of a new genetic study that found "LADA shares genetic features with both type 1 (HLA, INS VNTR, and PTPN22) and type 2 (TCF7L2) diabetes, which justifies considering LADA as an admixture of the two major types of diabetes."

ADOPT finds doubled incidence of Fractures in Women Taking Avandia Compared to Those Taking Metformin after Four Years

Page Changed: Actos and Avandia--Dangerous Drugs

The ADOPT study found almost twice as many fractures in women taking Avandia as in those taking metformin and almost three times as many fractures in this group than in those taking glyburide.

Fractures were in the arms and legs mostly. This duplicates a similar finding for Actos in an earlier study.

Folks, please do not take these dangerous TZD drugs, Avandia and Actos, which work by converting bone stem cells to fat cells and hence leaving your body with fewer cells available to repair your bones.

New Blood Sugar Calculator: ADAG A1c to mmol/L or mg/dl

Page Added: Blood Sugar/A1c Calculator

This handy calculator converts A1c to average blood glucose given either in mmol/L or mg/dl.

The formula used is the new ADAG formula based on CMGS measurements.

Study: FPG 100-110 mg/dl compared to 110-124 mg/dl for cardiovascular markers.

Page Changed: How Blood Sugar Control Deteriorates

Added discussion of a study which analyzed prevalence of cardiovascular risk factors broken out by sub groups of fasting plasm glucose in a group of 344 people. This study found that people with FPG > 110 mg/dl (6 mmol/L) had the same incidence of metabolic syndrome and cardiovascular markers as people with full fledged diabetes. Those with FPG between 100 and 110 mg/dl were far more normal. This suggests that early diabetes complications (i.e. cardiovascular disease) may be more reversible if treated before fasting blood sugar goes over 110 mg/dl (6 mmol/L).

WHI Vitamin D/Calcium Supplementation Doesn't Decrease Diabetes Incidence

Page Changed: Supplements That Work

Added link to results from Womens Health Initiative Calcium/Vitamin D supplementation arm which found no impact on the development of diabetes from supplementing Vitamin D at 400 IU and Calcium at 1000 IU a day.