Risk Quantified For Non-Diabetic A1cs and Heart Attack Risk
The Atherosclerosis Risk in Communities study tracked 11,092 black or white adults who did not have a history of diabetes or cardiovascular disease. for 15 years. It found no association between fasting blood sugar and risk of heart disease, but A1c was a different story. The The table below summarizes the correlation of baseline A1c with the risk of developing cardiovascular disease.Multivariate-Adjusted Hazard Ratio
5%: 0.96 (0.74-1.24)
5% to < 5.5%: 1.00 (reference)
5.5% to < 6%: 1.23 (1.07-1.41)
6% to < 6.5%: 1.78 (1.48-2.15)
≥ 6.5%: 1.95 (1.53-2.48)
Glycated Hemoglobin, Diabetes, and Cardiovascular Risk in Nondiabetic Adults. Elizabeth Selvin et al.NEJMVolume 362:800-811. March 4, 2010 Number 9.
Keep in mind that because these subjects were probably diagnosed as "non-diabetic" using a fasting glucose test many of those with the higher A1cs probably were diabetic at the study outset based on post-meal values. If you are recently diagnosed with diabetes and have no signs of heart disease, your risk/A1c ratio should be similar if not identical to those shown here.
