tag:blogger.com,1999:blog-77445801426105761012024-02-21T10:12:11.329-08:00Updates to Blood Sugar 101Use this blog to track updates to the Blood Sugar 101 web site.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.comBlogger265125tag:blogger.com,1999:blog-7744580142610576101.post-24655392040152182832021-05-06T10:11:00.003-07:002021-05-06T16:35:45.163-07:00Special Considerations for People with COVID-19 Related DiabetesPage Added: <a href="https://www.bloodsugar101.com/covid-19-related-diabetes" target="_blank">COVID-19 Related Diabetes</a><div><br /></div><div>Added a new page for people who have been given a diabetes diagnosis shortly after having a COVID-19 infection. Pointed out that COVID-19 may damage the pancreas in a way that produces a Type 1, rather than a Type 2 Diabetes. Explains the importance of getting the correct diagnosis to avoid a potentially fatal case of diabetic ketoacidosis. </div><div><br /></div><div>Describes a possible approach to helping with high blood sugars caused by dexamethasone treatment. </div>Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-22820412187227741662020-06-24T07:07:00.000-07:002020-06-24T07:07:00.896-07:00Metformin Lowers Mortality of Covid-19 in Women but Not Men<h5 class="font_5">
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Metformin was seen to decrease deaths among diabetic and obese women by 21-24% though not in men. The study analyzed a UnitedHealthcare database of 73,000 patients with COVID-19, but it focused on 6,000 who had obesity or diabetes.<br /></div>
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This apparently is because the drug has a different effect on women's immune systems than on men's. In women's it apparently damps down inflammation.<br /></div>
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<span style="text-decoration-line: underline;"><a dataquery="dGV4dExpbmtfa2J0ZmdkemQ=" href="https://www.blogger.com/null">https://www.medrxiv.org/content/10.1101/2020.06.19.20135095v1</a></span></div>
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This newspaper report goes into more detail:<br /><br /><a href="https://www.startribune.com/university-of-minnesota-s-large-covid-19-study-finds-new-drug-targets/571430922/">https://www.startribune.com/university-of-minnesota-s-large-covid-19-study-finds-new-drug-targets/571430922/https://www.bloodsugar101.com/metformin</a></div>
Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-90485780200882118242020-05-06T16:13:00.002-07:002020-05-06T16:13:44.671-07:00New GWAS Study identifies Type 2 Diabetes Genes in East Asian PopulationsPage Changed:<br />
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Text Added: <a href="https://www.bloodsugar101.com/the-real-causes-of-type-2-diabetes"> The Real Causes of Type 2 Diabetes</a><br />
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East Asian populations have some of the same diabetes genes as the ones described above, but a 2020 gene wide study identified yet another set of Type 2 diabetes genes found only in that population as well as variations that explain why diabetes is more prevalent in East Asians whose weight is closer to the normal range.<br /><br /><span style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: 0px 0px; background-repeat: initial; background-size: initial; border: 0px; margin: 0px; outline: 0px; padding: 0px; text-decoration-line: underline; vertical-align: baseline;"><a data-content="http://dx.doi.org/10.1038/s41586-020-2263-3" data-type="external" href="http://dx.doi.org/10.1038/s41586-020-2263-3" rel="noopener" style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: 0px 0px; background-repeat: initial; background-size: initial; border: 0px; cursor: pointer; margin: 0px; outline: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank">Cassandra N. Spracklen, et al. Identification of type 2 diabetes loci in 433,540 East Asian individuals. Nature, 2020; DOI: 10.1038/s41586-020-2263-3 https://www.nature.com/articles/s41586-020-2263-3</a></span></div>
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Explained in <span style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: 0px 0px; background-repeat: initial; background-size: initial; border: 0px; margin: 0px; outline: 0px; padding: 0px; text-decoration-line: underline; vertical-align: baseline;"><a data-content="https://www.sciencedaily.com/releases/2020/05/200506133631.htm" data-type="external" href="https://www.sciencedaily.com/releases/2020/05/200506133631.htm" rel="noopener" style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: 0px 0px; background-repeat: initial; background-size: initial; border: 0px; cursor: pointer; margin: 0px; outline: 0px; padding: 0px; text-decoration-line: none; vertical-align: baseline;" target="_blank">Science Daily: First-in-kind study reveals genetic markers of type 2 diabetes in East Asians</a></span></div>
Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-88972444981616372252020-02-13T08:32:00.004-08:002020-02-13T08:32:50.588-08:00Added info about cannabis and hunger to the "Help for when you can't control your eating" PagePage changed: <a href="https://www.bloodsugar101.com/how-to-stick-to-your-diet">https://www.bloodsugar101.com/how-to-stick-to-your-diet</a><br />
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Text added: Cannabis and CBD can make you very hungry. Now that cannabis is legal in many states we are hearing a lot of buzz about its medical benefits and especially those attributed to its CBD component. CBD does not get people high, but it has definite physiological effects, and one of them is to make people very hungry. This is helpful for people undergoing chemotherapy, who need to eat, but can be a problem for the rest of us.<br />
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Note that many products sold outside of dispensaries claiming to contain CBD contain so little that they have no physiological effect. Hunger is only an issue with the higher CBD strains sold at dispensaries. That said, even cannabis strains without CBD can give people fearsome attacks of the munchies a few hours after they are consumed. The reason for this turns out not to be fluctuating blood sugars, as people used to believe, but because there are components in certain cannabis strains--particularly those with indica genetics--that stimulate cannabinoid receptors in the gut in ways that activate the brain's hunger center. <br />
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The good news is that there are other THC-containing strains that do not provoke a hunger response. Some Sativa strains can actually dampen hunger. If you live in a place where cannabis is legal, you will just have to experiment until you find a strain that doesn't sabotage your diet.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-44057689183459538182019-12-22T11:37:00.000-08:002019-12-22T11:37:02.842-08:00Pancreatitis after taking GLP-1 analog drugs linked to carrier status for hemochromatosis and cystic fibrosisPage Changed <a href="https://www.bloodsugar101.com/glp-1-agonists">Glp-1 Agonists</a><br />
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Text Added: <br /><br />NEW! Pancreatitis after taking these drugs is more likely to occur in people who are carriers of the Cystic Fibrosis or Hemochromatosis gene.
Research published in 2018 suggests that people who are carriers or the genes for Cystic Fibrosis or Hemochromatosis may be at more risk for the pancreatitis caused by this family of drugs. Since these people are carriers, they are not diagnosed with these conditions, but if they have children with others who also carry these genes their children have a significant risk of inheriting these conditions.
It turns out that these genes, in carriers, may have subtle effects on the pancreas, which may explain why drugs that further irritate the pancreas may cause painful and possibly dangerous inflammation of the organ.<br />
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https://diabetes.diabetesjournals.org/content/67/Supplement_1/2296-PUBJennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-46102590865599387912018-08-02T12:56:00.002-07:002018-08-08T05:18:38.337-07:00The Whole Blood Sugar 101 Site is Moving<span style="background-color: white; color: #474b4e; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14px;">UPDATE: As of August 8, 2018 the move to the new host has been completed. </span><br />
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<span style="background-color: white; color: #474b4e; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14px;">After 13 years, the software that runs the Blood Sugar 101 site was showing its age, so I moved it to a new, much more easy to manage host. URLS with "bloodsugar101.com" now go directly to the new host, but the page URLS ( for example: /912423325.php) will come up as "page not found" as the pages now have new identifiers. The redesigned menus should make it easier to find what you are looking for. </span><br />
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<span style="color: #474b4e; font-family: arial, tahoma, helvetica, freesans, sans-serif;"><span style="background-color: white; font-size: 14px;">If you click on any of the articles, which now display in a blog format, you will see a magnifiying glass search icon in the upper right hand corner which you can use to search the new site. There is also a google search you can find under "More" on the top menu. </span></span><br />
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<span style="background-color: white; color: #474b4e; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14px;">The old site at http://www.phlaunt.com/diabetes now redirects to the new website. </span><br />
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<span style="background-color: white; color: #474b4e; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14px;">This change will allow me to make the new site secure, which I hope will help it rise again in Google searches. Not having a secure site has become a problem as Google doesn't like such sites and Chrome will warn users away from them.</span><br />
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Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-56989683088485463642017-12-19T08:25:00.000-08:002017-12-19T08:25:09.607-08:00Generic repaglinide may act much more slowly than Prandin, making hypos more likelyPage Changed: <a href="http://www.phlaunt.com/diabetes/25311847.php">Glipizide, Glyburide, Repaglinide etc: Drugs that Stimulate Insulin Secretion</a><br />
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Generic Repaglinide May Not Have the Same Speed of Action as Name Brand Prandin</h4>
By using a FreeStyle Libre Flash Glucose Monitor, I was able to see exactly how repaglinide works for me, and discovered that it appears to activate much more slowly than the brand name Prandin version that I used to use before the drug was available as a generic. My pharmacist confirms this is likely. If your insurance will let your doctor prescribe the name brand version, use it. Otherwise, you may have to take repaglinide 1 to 2 hours before eating to get it to lower the peak caused by a meal. If you take it at meal time, as directed by the label, you may get a peak one hour after eating, followed by a potentially serious low an hour or two later. The branded version can be taken at mealtimes and peaks at 1 hour after it is taken.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-44735561175657455222017-12-15T08:07:00.002-08:002017-12-15T08:07:31.453-08:00A Link to the Ongoing Reivew of the FreeStyle Libre CGM Added to Main SitePage Added: <a href="http://www.phlaunt.com/diabetes/51335268.php">Testing the FreeStyle Libre Flash Glucose Monitor</a><br />
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I am reporting on my trial of the FreeStyle Libre Flash Glucose Monitoring System that Abbott, the manufacturer, sent me for review. Disclosure: I received the $70 reader and two $40 sensors for free. I have subsequently filled a prescription and paid for three more sensors myself. <br /><br />To read my reports in sequence, visit this blog page:<br /><a href="http://diabetesupdate.blogspot.com/2017/11/im-testing-freestyle-libre-flash.html">http://diabetesupdate.blogspot.com/2017/11/im-testing-freestyle-libre-flash.html</a><br /><br />When my trial concludes I will write up a page about this extremely useful device, which I think could revolutionize the way that people with Type 2 Diabetes use the <a href="http://www.phlaunt.com/diabetes/how.php">Test, Test, Test Strategy</a> for acheiving normal blood sugars.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-17741102604072273642017-10-18T09:54:00.001-07:002017-10-18T09:54:45.158-07:00New Fast Acting Insulin Fiasp and new GLP-1 Agonist Semaglutide Mentioned in Relevant Web PagesPages changed: <a href="http://www.phlaunt.com/diabetes/18538438.php">GLP-Agonists</a> and <a href="http://www.phlaunt.com/diabetes/15478720.php">Insulin for Type 2 Diabetes</a><br />
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Brief mention made of the upcoming approval of semaglutide, the first GLP-1 agonist in pill form and of Fiasp, a new fast-acting insulin which is similar to Apidra in that it can be injected just after eating and still be effective.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-88490281318360541022017-05-25T12:49:00.002-07:002017-05-25T12:49:50.719-07:00Link Added to Gary Scheiner's Review on the Afrezza Page of Blood Sugar 101 Page Changed: <a href="http://www.phlaunt.com/diabetes/42243240.php">Inhaled Insulin: Afrezza </a><br />
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A review of Afrezza written by Gary Scheiner, a Certified Diabetes Educator whose book I have often recommended, came out in May of 2017 and may be helpful to people considering trying this insulin. I trust Scheiner a lot more than I do random people tweeting, who may or may not be on the payroll of the company making this stuff. You can read his review in his newsletter, <a href="http://integrateddiabetes.com/my-review-of-afrezza-fast-acting-inhaled-insulin/amp/">HERE</a>. Unfortunately, there is still no one with this kind of preexisting credibility in the online diabetes community reporting on their use of Afrezza for Type 2 Diabetes. This may simply be because doctors are so resistant to prescribing fast acting insulin to people with Type 2 diabetes. Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-63765941309457291182017-05-16T12:57:00.000-07:002017-05-16T12:57:28.382-07:00FDA Puts Warning of Doubled Risk of Amputation on Invokana LabelPage changed: <a href="http://www.phlaunt.com/diabetes/36474059.php">SGLT2 Inhibitors, Farxiga, Invokana, Jardiance.Dangerous New Drugs</a><br />
Note: "Questionable" has been changed to "Dangerous in this page title.<br />
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Doubled Risk of Lower Limb Amputations</h4>
On May 16, 2017 the FDA ordered that a black box warning be added to the prescribing information for Invokana saying that it doubled the risk of experiencing an amputation. You can read the report about this very important warning <a href="http://www.medscape.com/viewarticle/880059">in this Medscape news bulletin.</a><br />
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<br />Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-27486934370019242362017-02-13T15:45:00.003-08:002017-02-13T15:45:35.777-08:00EMA Orders SGLT-2 Drug Labels to Warn of Increased Risk of Lower Limb Amputations<h4>
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Increased Risk of Lower Limb Amputations</h4>
As reported on <a href="http://www.medscape.com/viewarticle/875649">Medscape</a> The European Medicines Agency (EMA) which is the European equivalent of the FDA announced on February 10, 2017 that a warning stating that the sodium glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes may increase the risk for lower-limb amputation should be included in the prescribing information for all drugs in this class.<br />
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In Medscape's words, "The warning from EMA's Pharmacovigilance Risk Assessment Committee (PRAC) issued today cites data from two ongoing clinical trials with canagliflozin (Invokana, Vokanamet, Janssen) in patients at high risk for cardiovascular events, Canagliflozin Cardiovascular Assessment Study (CANVAS) and a related study of renal end points, CANVAS-R."<br />
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Quoting the EMA the article points out that "In a 4.5-year interim analysis of CANVAS, the independent monitoring committee for the trial found that the rate of amputations per every 1000 patients was equivalent to seven for 100 mg/day and five for 300 mg/day of canagliflozin compared with three per 1000 patients taking placebo. Most of the amputations were of toes." Note that this means that there were from one and two thirds more to more than twice as many amputations in the group taking the drug as occurred in the placebo group. <br />
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As you can see if you read the comments to the Medscape new release, some people claiming to be doctors and a pharmacist immediately argued that this was because the patients given the SGLT-2 inhibitors were sicker and more likely to have amputations. People posting comments on Medscape are not required to reveal if they are on the payroll of the companies who are earning several billion dollars a year selling these heavily advertised new drugs. Nor are they required to validate their identity, so any employee of a drug company could post these comments using a made up doctor's name. <br />
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Lest you be swayed by their arguments against believing the EMA's experts, note that this data was from a controlled study. This means that both the group taking the drug and the group taking a placebo were matched for characteristics which would have included their blood sugars, age, and time since diagnosis. Since the groups had the same characteristics, the higher rate of amputations is very likely to be a result of something the drug does to the blood supply of the toes. The EMA doesn't lightly decide to add a serious warning to the label of a drug.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-14442744122840677462017-02-13T15:15:00.003-08:002017-02-13T15:15:42.653-08:00New Brazilian Portuguese version of the "How To Lower Your Blood Sugar" Flyer uploadedPage Changed: <a href="http://www.phlaunt.com/diabetes/14045524.php">How to Lower Your Blood Sugar</a><br />
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Added a link to a Brazilian Portuguese translation of the flyer. <br />
The PDF can be downloaded here: http://www.phlaunt.com/diabetes/BrazilianPortugueseFlyer.pdf .Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-65635186305020625482017-01-20T11:50:00.000-08:002017-01-20T11:50:37.984-08:00A link to The Blood Sugar 101 Monthly Challenge Has Been Added to Our Main Web SitePage Added:<a href="http://www.phlaunt.com/diabetes/48493849.php">Hold Yourself Accountable - Join the Blood Sugar 101 Monthly Challenge</a> <br />
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This page links to the monthly diet/blood sugar challenge that was created in response to requests from members of our <a href="http://www.phlaunt.com/diabetes/48493849.php">Blood Sugar 101 FaceBook Page</a> .<br />
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A new challenge will start each month. The page describes how the challenge works and how we hope to collect useful real-world experience data from it.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-81414362398057563372016-10-27T12:16:00.001-07:002016-10-27T12:16:14.177-07:00New Page Added: Common Phosphate Additives Damage Your Kidneys and Cardiovascular SystemPage Added:<a href="http://www.phlaunt.com/diabetes/47759082.php">Common Phosphate Additives Damage Your Kidneys and Cardiovascular System</a>
This new page on the main Blood Sugar 101 Web Site combines information that was posted in several blog posts in 2013. It is now also linked to from the Diabetic Kidney Disease page.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-45758528517661021882016-09-30T11:28:00.001-07:002016-09-30T11:28:42.455-07:00I report about my bad experience with Intermittent FastingPage Changed: <a href="http://www.phlaunt.com/diabetes/43067994.php">Is Your Low Carb Diet Safe?</a><br />
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8. <b>Intermittent Fasting--Another Way to Provoke the Starvation Response and Ruin Your Metabolism</b>. Intermittent fasting diets like the 5:2 Diet are very popular now but most of us who have tried them for extended periods of time have learned they have all the problems seen with other extreme diets, though they don't seem like starvation diets, as you can eat "normally" when not fasting.<br />
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Encouraged by the success reported by some people I trust, I tested out a very strict 5:2 Fast Diet for two years. It took the whole two years for me to see the toll that this kind of dieting took on my body. During the two years I participated daily in an active online fasting-support group where I observed that the ultimately negative outcome I experienced was what most of the dedicated participants in the online group experienced: Very good weight loss results for the first seven months were followed by a sudden reversal where I first stalled and then then began to gain weight relentlessly eating exactly the way I'd been eating while losing so quickly. Worse, my appetite went out of control and by the end of the two years I had developed what felt like a binging disorder.<br />
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This was something I had never before experienced in 65 years of controlling my weight with various diet approaches, including 11 years of maintaining a substantial weight loss achieved eating a very low carb diet featuring occasional days off. At the end of my 2 years of intermittent fasting I ended up with far more jiggly subcutaneous fat than I had started with, even though I ended up at the same weight I started at.<br />
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I believe this happened because fasting lowered my estrogen levels dramatically.<br />
This was evidenced by my developing menopausal symptoms after a year on the diet--a decade after last experiencing them, at the same time as the diet had, indeed gotten rid of subcutaneous tummy fat. <br />
It took me a good year to get back to having a normal relationship with my appetite. During that year I had to give up entirely on dieting in any way. The tummy fat seems to have moved in permanently.<br />
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This experience was very much like what I saw others experience, too, including personal friends and people on the online support group. To me this suggests that long-term intermittent fasting changes your brain chemistry and hormonal balance in a way that makes it much more likely that you will eventually run into this kind of problem. <br />
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If you are considering trying intermittent fasting be aware that all the research that is currently used to promote fasting by the usual suspects who get rich selling celebrity doctor diet books is based on <i>very short studies</i> which lasted only a few weeks or, at most, months. Almost all the studies on fasting looked at the physiological changes caused by very short stints of medically supervised complete fasting. Almost none examine the kinds of intermittent fasting dieters use in the currently popular diets like 5:2. The truth is, there is zero data about the long term experience of intermittent fasters. <br />
The sad outcomes most people in my online fasting support forum experienced and my own results suggest that the outcomes over extended periods of time are mostly poor. <br />
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Eating a <i>low carb</i> intermittent fasting diet doesn't seem to produce better results, either, based on the reports of those on the fasting support group, who were eating that way.Those dieters stalled and regained on very low carb diets too.<br />
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My experience and that of participants in low carb diet support groups suggest that those who figure out a way to cut carbs in a way that doesn't make them feel deprived are able to stick to their diets for far longer with much better results and, most importantly, without the rebound hunger and metabolic slowdown that is so characteristic of more extreme diets. It's worth noting, however, that my polling of those who ate low carb diets for extended periods after achieving weight loss goals showed that most of the successful dieters who did this maintained eating at a non-ketogenic intake level--one close to 110 g a day. It is possible that extended ketogenic dieting may also provoke the starvation response in some people.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-40095166006908228262016-08-22T08:54:00.001-07:002016-08-22T09:02:37.185-07:00Split "A Diabetes Diet is Different From a Weight Loss Diet" Page into Two PagesPage changed: <a href="http://www.phlaunt.com/diabetes/14046989.php">A Diabetes Diet is Diffferent from and Easier Than a Weight Loss Diet</a><br />
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Split and new page created from second half: <a href="http://www.phlaunt.com/diabetes/47188105.php">Strategies for Sticking to Your Diabetes Diet for Decades</a><br />
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Minor changes and updates were made to the text of both pages.<br />
<br />Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-89554457605565635222016-08-14T09:30:00.004-07:002016-08-14T09:30:59.409-07:00New Page Added to Blood Sugar 101Page Added: <a href="http://www.phlaunt.com/diabetes/47119160.php">When Your Doctor Isn't Helpful</a>Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-73547829907040475922016-08-14T06:57:00.001-07:002016-08-14T06:57:24.461-07:00"You Didn't Eat Your Way to Diabetes" Page Split into Two PagesPage Changed: <a href="http://www.phlaunt.com/diabetes/14046739.php">You Didn't Eat Your Way to Diabetes: The Real Causes</a><br />
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Split into two pages, the second page is now:<br />
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<a href="http://www.phlaunt.com/diabetes/47101698.php"> Obesity Doesn't Cause Diabetes--Diabetes Genes Causes Obesity </a><br />
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There is a link on the bottom of the first page to the second.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-87215889283664818842016-08-08T09:06:00.000-07:002016-08-08T09:06:09.129-07:00Page Changed: <a href="http://www.phlaunt.com/diabetes/14045678.php">Research Connecting Blood Sugar Level to Organ Damage</a><br />
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<b>NOTE:</b> It is important to keep in mind that the readings people get on glucose tolerance tests may be lower at two hours after consuming the glucose than the readings they get while eating meals containing carbohydrates that require digestion. The speedy absorption of the glucose that occurs during a glucose tolerance test often causes reactive hypoglycemia in people with prediabetes, giving them what look like normal numbers. But in daily life they may be experiencing blood sugars well above normal for an hour or two after slower-digesting meals. Unless you live on a diet of pure glucose, this is an important finding. Because it is the number of hours your nerves spend exposed to high blood sugars that appears to damage them.<br />
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Sadly, there are <i>no</i> studies where subjects with neuropathy were given meal tests rather than the highly artificial oral glucose tolerance test. However, anecdotal reports from people with neuropathy who have lowered their post meal blood sugars suggest that keeping blood sugars under 140 mg/dl (7.8 mmol/L) at one hour after eating meals can slowly reverse neuropathy.<br />
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Unfortunately, since most doctors are not aware that it is possible reverse neuropathy by lowering blood sugars to normal levels or believe it is impossible for people with diabetes to lower their blood sugars to normal levels at all, few doctors suggest that patients with neuropathy treat it by striving to achieve normal blood sugars. Instead, they prescribe the very dangerous brain drugs, gabapenin (Neurontin) and pregabalin (Lyrica) which may relieve neurological pain to some extent but don't in any way heal damaged nerves. These drugs can have devastating side effects, so before you try one, try lowering your blood sugars to normal levels for a few months. You can learn how to do that <a href="http://www.phlaunt.com/diabetes/how.php">HERE</a><br />
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Further down, added:<br />
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The reason slightly elevated fasting blood sugars correlate with beta cell dysfunction and/or destruction is almost certainly that people with slightly elevated fasting blood sugars who eat high carbohydrate meals are experiencing high, and often long lasting, blood sugar spikes after each meal they eat. ... It is almost certainly those high <i>post meal</i> readings that go along with elevated fasting levels that cause the glucose toxicity that damages organs and causes complications, not the slightly higher than normal fasting blood sugars.This conclusion is backed up by the experience of those of us with diabetes who have kept our post-meal blood sugars under 140 mg/dl after meals for a decade or more. We generally find that our diabetes does <i>not</i> progress and that we do not develop the classic diabetic complications.<br />
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Other minor changes have been made and dead links repaired.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-45393793179132762602016-08-05T11:44:00.000-07:002016-08-05T11:44:06.263-07:00Page Changed: <a href="http://dietmakeupcalc.php/">Nutritional Calculator Results Page</a><br />
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This calculator will not prescribe a diet of under 1000 calories a day, because very low calorie diets are not healthy or sustainable over the long term for most people.<br />
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Very low calorie diet <i>do</i> take off the pounds, however they tend to result in the dieter burning off too much muscle tissue. This can harm the heart. If you diet at a sub-1,000 calorie level you are also likely to slow your metabolism. That makes it difficult to get to your goal, and worse, it makes it much easier to regain weight even if you start eating at a more reasonable calorie level. <br />
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The very low calorie diet also is very likely to change your brain chemistry in a way that raises the hormones that make you hungry. When this happens you will only be able to maintain your weight loss by living in a state that feels like you are always starving. <br />
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Losing weight on a higher calorie low carb diet, though it may take more time to get to goal, ensures that you will be able to maintain your weight loss by eating at the level predicted for maintaining your new weight. It also keeps you from experiencing the rebound hunger that explains why so many people who lose a lot of weight on low calorie diets gain it all back and more. <br />
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Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-61230870114907975442016-08-05T10:40:00.001-07:002016-08-05T10:40:06.864-07:00Tresiba is worth a try if you are having problems with controlling your fasting blood sugarPage Changed: <a href="http://www.phlaunt.com/diabetes/17561156.php">Why Is My Blood Sugar Higher in the Morning</a><br />
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Added text: <span style="background-color: white; color: #303030; font-family: arial, helvetica, sans-serif;">Another alternative is to try the new insulin, Tresiba, if your insurance will cover it. Some people are reporting much smoother blood sugars when taking this new basal insulin.</span>Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-8182398820159893232016-07-28T11:42:00.004-07:002016-07-28T11:42:46.818-07:00Lixinitide approved in the U.S. under the name Adlixin not LyxumiaPage Changed: <a href="http://www.phlaunt.com/diabetes/18538438.php">GLP-1 Agonists</a><br />
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Changed references to Lyxumia to "Adlixin" as that is the name that is being used for this dangerous, not particularly effective "me too" drug in the U.S. generic name lixisenatide, which was just approved by the rubber stamp FDA. It is not being trade named Lyxumia, which is its name in the rest of the world. The change suggests it hasn't been selling well or getting good reviews under the old trade name.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-8267305164681820762016-05-09T07:43:00.002-07:002016-05-09T07:44:29.158-07:00A Large Epidemiological Study Confirms Actos/Bladder Cancer Link<b><br /></b>
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Page Changed</b>:<a href="http://www.phlaunt.com/diabetes/18554346.php">Actos and Avandia: Dangerous Diabetes Drugs</a><br />
<b>Text Updated: </b>Actos Is Proven to be Associated with A Higher Rate of Bladder Cancer<br />
On Sept 17, 2010, the <a href="http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm226244.htm">FDA announced</a> that it was conducting a safety review of Actos, because prelimnary (5 year) results from a 10 year study found "...there was an increased risk of bladder cancer in patients with the longest exposure to Actos and in those with the highest cumulative dose of the drug.<br />
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In June of 2011 the <a href="http://www.fda.gov/Drugs/DrugSafety/ucm259150.htm">FDA confirmed</a> FDA confirmed that there <i>was</i> a heightened risk of bladder cancer with Actos. Years later, in May of 2016 a study published in the high impact British Medical Journal, which studied the records of 145,806 patients again concluded that "Piaglitazone [Actos] is associted with an increased risk of bladder cancer." This association was only true for Actos, not Avandia, suggesting something about the drug itself, not the class of drugs, was at fault. <br />
<a href="http://www.bmj.com/content/352/bmj.i1541"></a><br />
Pioglitazone use and risk of bladder cancer: population based cohort study. Marco Tuccori, et al.<br />
BMJ 2016; 352 doi: http://dx.doi.org/10.1136/bmj.i1541. However, doctors can still prescribe Actos.Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0tag:blogger.com,1999:blog-7744580142610576101.post-51594323422076863862016-04-22T08:56:00.001-07:002016-04-22T08:56:55.419-07:00FDA Warns Onglyza and Nesina Raise Risk of Heart Failure Confirming Earlier StudyPage Changed: <span style="background-color: white; color: #303030; font-family: "verdana" , "arial" , "helvetica" , sans-serif; font-size: 16px; text-align: center;"><a href="http://www.phlaunt.com/diabetes/18538604.php">DPP-4 Inhibitors Januvia, Onglyza, Trajenta, Combiglyze, Janumet, and Jentadueto</a></span><br />
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In April of 2016 After another year of dallying around, during which unknown numbers of patients were probably injured by this drug and a new one in the same class, Nesina, the FDA issued a safety alert stating, <br />
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An FDA safety review has found that type 2 diabetes medicines containing saxagliptin and alogliptin may increase the risk of heart failure, particularly in patients who already have heart or kidney disease. As a result, FDA is adding new warnings to the drug labels about this safety issue.</blockquote>
However, in line with the FDA's policy of putting the business interests of the companies it regulates ahead of the interests of the people who take these drugs, the FDA's recommendation to doctors was merely, <br />
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Health care professionals should consider discontinuing medications containing saxagliptin and alogliptin in patients who develop heart failure and monitor their diabetes control.</blockquote>
This is shameful! Why should any doctor wait until a patient taking a suspect drug has already developed heart failure--a condition that usually limits their life expectancy to a few years--before taking them off it. There are multiple studies confirming that these drugs appear to be <i>promoting</i> the developement of heart failure.You can read the FDA's safety alert noting the label change <a href="http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm494252.htm">HERE</a></div>
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If you are prescribed any of these drugs, remember that few busy doctors are able keep up with changes to the labels of all the drugs they prescribe. And as the FDA allows these suspect drugs to be sold, they will continue to be prescribed. This kind of FDA response is in line with its policy of putting the business interests of the drug companies it is supposed to regulate above those of drug users. </div>
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Jennyhttp://www.blogger.com/profile/17384082448952856117noreply@blogger.com0