This blog tracks updates to the Blood Sugar 101 Web site.

Wednesday, May 27, 2009

Reference Removed: Metformin May Prevent Beta Cell Apoptosis

Page Changed: Metformin, Acarbose, Sulfonylureas: The Truth About Oral Diabetes Drugs

Removed citation to human pancreas autopsy study with findings that metformin might help prevent beta cell apoptosis (cell suicide). Reading the full study made it clear that the researchers were not discussing the actual impact of metformin taken as a drug on humans, but instead describing a highly artificial situation created in cultured cells taken from dead pancreata and bathed in fat and a metformin solution.

This is the study:
Autophagy in human type 2 diabetes pancreatic beta cells M. Massini et al. Diabetologia Volume 52, Number 6 / June, 2009, DOI 10.1007/s00125-009-1347-2.Pages 1083-1086

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